Recombinant Protein - A

 

Protein A links to to the cell wall of most bacterium Staphylococcus aureus. It has high affinity to IgG from various species, and interacts with antibodies like human IgG1, IgG2, IgG4, IgM, IgA, IgE, therefore ideal for purification process of most mAbs.

With high selectivity and good stability properties, protein A is currently the preferred ligand for purification of antibodies.

 

Our Protein A is specifically modified for commercial scale chromtraphic media applications. The clone was modified for ideal media performance, the protein is manufactured on our propieatary E. coli platofrm and purified by HPLC reaching highest purity levels.

 

With improved resistance to cleaning, our Protein A has strong resistance to alkali CIP thus allow longer media usage, longer production campaigns and simplified manufacturing processes, resulting in production down time and media change reduction, ideal media performance, yield improvement and overall costs reduction.

 

Advantage

Application

Cost saving – improved CIP resistance, optimal media performance

 

Time saving – reduce media changes, longer campaigns, reduced down time

 

Yield improvement – reduce final product loss, optimized purification

 

Optimal – modified clone, comply with media variation of particle sizes, density and porosity

 

Pure – increased specificity, no contaminants, better performance

 

Flexible – supplied in powder and liquid forms

Animal origin free, manufactured under cGMP, ISO and Pharma standards

Production / purification of mAbs

 

In-process testing

 

 
 

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Medxbio Pte Ltd

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